GSK invests a further S$77mil to enhance antibiotic manufacturing facility in Singapore

Issued: Singapore

GSK today announced it will invest an additional £38M (S$77M) in its world-class antibiotic manufacturing plant at Quality Road in Singapore, building on its initial investment of S$60M committed in 2012.

The Quality Road plant is GSK’s sole production site for amoxicillin; the active compound used in the manufacture of antibiotics that are widely prescribed for the treatment of bacterial infections.

The new investment will be used to construct an additional downstream isolation facility for GSK’s state-of-the- art enzymatic manufacturing facility at Quality Road.

This will increase production by 50% and help the company meet the growing demand for antibiotics in emerging markets.

The investment marks an important milestone in GSK’s enduring partnership with Singapore’s Economic Development Board (EDB) and is a key element of the GSK-EDB 10-year Singapore Manufacturing Roadmap announced in 2012.

The use of enzymatic technology over chemical processes in the production of amoxicillin will also reduce our carbon footprint by up to 25%.

The improved process involves fewer steps under milder conditions and utilises less organic solvents, resulting in the elimination of almost 80% of the organic waste associated with the older chemical process, while maintaining our industry leading product quality standards.

This sustainable approach to the manufacture of amoxicillin is consistent with GSK’s commitment with the EDB to improve the efficiency of pharmaceutical and fine chemical manufacture in Singapore.


Roger Connor, President of Global Manufacturing and Supply, GSK, said: GSK and Singapore have enjoyed a highly-productive partnership for over 50 years. This latest investment in sustainable manufacturing and our recent investment announced in October 2014 for a £19M (S$38.5M) continuous manufacturing facility in Jurong, which produces one of GSK’s key active pharmaceutical ingredients, demonstrates our commitment to ensuring that patients around the world receive the medicines they need and also underscores our shared vision with the EDB to improve the technical capabilities of Singapore’s biomedical science sector.

Yeoh Keat Chuan, Managing Director of the Singapore Economic Development Board (EDB) said: Singapore is a leading global location for best-in-class biopharmaceutical manufacturing. This project, which is part of the GSK-EDB 10 year manufacturing roadmap, is aligned with Singapore’s vision to become a key site for research, development and industrialisation of cutting edge pharmaceutical manufacturing technologies. This will further enhance the efficiency and competitiveness of Singapore. We are proud to be a partner to GSK in creating the future of pharmaceutical manufacturing.

Notes to editors

GSK
One of the world’s leading research-based pharmaceutical and healthcare companies – is committed to improving the quality of human life by enabling people to do more, feel better and live longer. For further information please visit www.gsk.com.

About GSK Singapore
Singapore is home to GSK’s Regional Headquarters (Emerging Markets & Asia Pacific), two global primary manufacturing and supply sites (Jurong & Quality Road) and a state-of-the-art vaccines plant (Tuas).

About the Quality Road Site
The Quality Road site was built in 1972 and officially opened on 3rd May 1973 by then Finance Minister, Mr Hon Sui Sen. Built at a cost of over S$32 million, the plant sits on a five-hectare site. The site was originally built to produce a range of newly discovered semi-synthetic penicillins and had both primary and secondary production facilities to make the final dose forms. Over time, the site developed as the single source of amoxicillin and monosodium ticarcillin within GSK, which are active compounds for the manufacture of two of GSK’s antibiotics.

GSK-EDB 10 year manufacturing roadmap
In 2012, GSK and Singapore’s Economic Development Board (EDB) jointly explored strategic investment options for GSK in Singapore that would be beneficial for both parties as part of their long-standing collaborative relationship. This led to the formation of a GSK-EDB 10 year Singapore Manufacturing Roadmap that aims to guide the investment decisions and developmental work to ensure manufacturing remains a competitive edge for both GSK and Singapore. This announcement is one of the collaborative areas in this 10-year roadmap.

GSK enquiries

Singapore media enquiries: Raymond Peter Francis +65 81256131
Director Communications, Asia Raymond.p.francis@gsk.com